Open mandibular condylotomy (osteotomy) with precision scaphoid staple osteosynthesis and meniscopexy. A description of the operation

The technical minutiae of the operation of open mandibular condylotomy and precision scaphoid staple osteosynthesis with meniscoplasty or meniscopexy is described and illustrated. The operation is regarded as an evolution of closed condylotomy described by Ward in 1961 and is indicated for those cases of severe and persistent temporomandibular joint pain and crepitus unresponsive to skilled conservative treatment over a reasonable time. The success of the procedure is probably the sequel of a partial denervation of the joint capsule associated with arthrotomy, the interruption of venous hypertension, the relocation of the mandibular condyle and enlargement of the joint space. The operation is also applicable to cases of active (and inactive) mandibular condylar hyperplasia wherein a condylar neck ostectomy and staple is used to ablate an active growth centre or correct a lesser degree of mandibular asymmetry.     

Some unusual oral lesions in HIV infection: Comments on the current classification

Of the numerous oral lesions reported in HIV-infected patients, four entities will be discussed in this paper: linear gingival erythema; cystic lymphoid hyperplasia of the parotid gland; oral non-Hodgkin's lymphoma; and oral squamous cell carcinoma. Based on the literature and the author's personal experience, it appears that linear gingival erythema is perhaps a specific HIV-associated periodontal lesion, but that insufficient data are available in the literature yet to classify this periodontal lesion as a lesion that is strongly associated with HIV infection. On the other hand, cystic lymphoid hyperplasia of the parotid gland has been rather widely reported and has characteristic histopathological features that would justify consideration of this lesion as highly indicative of an underlying HIV infection. Oral non-Hodgkin's lymphoma, at present regarded as a lesion ‘strongly associated with HIV infection’, is less characteristic in this respect and should merely be classified as ‘a lesion seen in HIV infection’. Oral squamous cell carcinomas, not included in the most recent International Classification of Oral Manifestations of HIV infection, should be listed in Group 3 of that classification, representing ‘lesions seen in HIV infection’. Further criteria should be developed that will enable distinctions to be made between lesions ‘strongly associated with’, ‘less commonly associated with’, and ‘seen in’ HIV infection.     

髁突增生与下颌骨畸形研究进展

1概述及流行病学情况 髁突增生（condylar hyperplasia），有文献称之为髁突肥大（condylar hypertrophy），髁突良性肥大（benign condylar hypertrophy）。本病是由于一侧髁突骨质增生而引起下颌骨不对称性畸形，在下颌骨不对称畸形中，其发病比例相当高，而国内文献却罕有这方面的报道。本文即针对该病的研究情况作一个综述。     

硝苯地平性牙龈增生组织中成纤维细胞增殖和胶原分泌

目的探讨硝苯地平对牙龈组织中成纤维细胞增殖和胶原分泌的影响。方法体外原代培养硝苯地平易感性牙龈组织和非易感性组织中人牙龈成纤维细胞。MTT法观察硝苯地平对细胞增殖的影响,酶联免疫吸附试验检测硝苯地平对细胞Ⅰ型胶原表达水平的影响。结果在第1,3,5天,硝苯地平易感性牙龈组织和非易感性组织之间Ⅰ型胶原合成和细胞增殖在统计学上均有显著性差异。结论细胞增殖明显和胶原合成增加可能和硝苯地平药物性牙龈增生机制有关。     

Diffuse but unilateral gingival enlargement associated with von Recklinghausen neurofibromatosis: a case report

BACKGROUND: An 8-year old girl was referred for diagnosis and treatment to the Department of Periodontology Oral Surgery of the University Hospital of Liège with an unusual clinical situation: a major, non-inflammatory, diffuse but unilateral enlargement of the interproximal, marginal and attached gingiva around all teeth of the right side of both the upper maxilla and mandible, whereas the alveolar process of the left side of upper and lower arches appeared strictly normal. METHOD: The clinical examination showed delayed eruption of some permanent teeth in the 1st and 4th quadrants. Except for its asymmetric occurrence, this gingival enlargement strongly resembled phenytoin-induced enlargement or gingival fibromatosis. This unilateral expression was evocative of a vascular or neurologic pathology. Several large "café-au-lait" spots were found disseminated on the body. Several selective surgical removals of thick gingival caps impairing the eruption of some permanent teeth were performed, and the removed tissues were histologically analyzed. RESULTS: Because of the presence of the large "café-au-lait" spots, a clinical diagnosis of Von Recklinghausen's disease was given and later confirmed several times by the histological analysis of the gingival biopsies. Now, 6 years later, this gingival enlargement due to the development of intra-gingival neurofibromas is stable and all permanent teeth have had a normal eruption, but alveolar bone growth has been partly impaired by the presence of the tumor. CONCLUSIONS: The present case of unilateral diffuse hyperplasia is a unique clinical expression of neurofibromatosis type I, a slowly evolving neurodermic dysplasia.     

DELFIA检测血清PSA、fPSA及fPSA/PSA在前列腺疾病诊断中的应用

目的：探讨双标记时间分辨荧光免疫分析(DELFIA)检测血清PSA、fPSA及fPSA/PSA在前列腺疾病诊断中的应用。方法：应用DELFIA法检测正常对照组(34例)、前列腺炎组(46例)、前列腺增生症组(123例)及前列腺癌组(39例)血清PSA、fPSA含量及fPSA/PSA。结果：前列腺癌组PSA、fPSA与其他三组比较差异均有显著性(P＜0.01),而其他3组之间比较差异显著性(P＞0.05);前列腺癌组fPSA/PSA明显降低,与其他3组比较差异均有显著性(P＜0.05)。结论：应用DELFIA检测PSA、fPSA含量及fPSA/PSA是提高前列腺疾病诊断与鉴别诊断更为有效的方法,尤其对前列腺癌诊断更有意义。     

血管平滑肌细胞表型转化的分子机制研究进展

血管内膜新生是血管成形术后再狭窄和动脉粥样硬化等心血管疾病的病理基础。血管平滑肌细胞（vascular smooth muscle cells,VSMCs）具有高度可塑性,在众多病理因素下常发生表型转化（phenotypic switch）,即由收缩型向合成型转化。研究表明,VSMCs表型转化促进其增殖和迁移,从而参与血管内膜新生形成。本文主要综述了VSMCs表型转化影响内膜新生的分子机制,为防治血管重塑性疾病提供理论依据。     

综合护理干预对前列腺增生症合并腹股沟疝术后自我护理及生活质量的影响

目的探究综合护理干预对前列腺增生症合并腹股沟疝术后自我护理及生活质量的影响。 方法选取2018年3月至2020年3月于新疆维吾尔自治区人民医院就诊的132例前列腺增生症合并腹股沟疝术后患者,采用随机表法分为对照组和观察组,各66例。比较2组患者术后恢复情况、并发症发生率以及2组患者在护理干预前、出院时的焦虑自评量表（SAS）、自评抑郁量表（SDS）、生活质量调查简表（SF-36）评分,出院时患者对护理工作的满意度调查结果。 结果观察组患者术后恢复时间均短于对照组（P<0.05）。观察组患者术后的并发症发生率（3.03%）远低于对照组术后并发症发生率（9.09%）（P<0.05）。2组患者出院时SAS、SDS评分均比干预前明显降低,且观察组显著低于对照组（P<0.05）。出院时,2组患者生理健康总评（PCS）和心理健康总评（MCS）评分均较干预前有所升高（P<0.05）,且观察组PCS和MCS评分显著高于对照组（P<0.05）。出院时,观察组患者对护理工作各项满意度的评分均显著高于对照组（P<0.05）。 结论综合护理干预对前列腺增生症合并腹股沟疝患者的术后自我护理有着极好的引导作用,患者能够尽快适应术后变化,进而调动患者的自主能动性,提高患者生活质量。     

经尿道前列腺电切术与经尿道双极等离子前列腺腔内剜除术的临床效果及其对患者性功能影响的对比分析

目的 比较经尿道前列腺电切术（TURP）与经尿道双极等离子前列腺腔内剜除术（TPKEP）治疗前列腺增生患者的临床效果,并分析其对患者性功能的影响。方法 选取我院2016年1月至2018年1月86例前列腺增生患者为研究对象,将实施经尿道双极等离子前列腺腔内剜除术的作为观察对象（TPKEP组,n=44）,将行经尿道前列腺电切术的患者作为对照组（TURP组,n=42）,收集两组患者的围手术数据和术后性功能状况资料并进行比较。结果 TPKEP组患者手术时间65.4±15.8 min、术中出血量231.3±77.5 mL及导管留置时间5.5±0.6 d,TURP组患者手术时间76.8±16.9 min、术中出血量346.2±81.4 mL及导管留置时间6.0±0.7 d,两组间的差异有统计学意义（P<0.05）。TPKEP组患者术后勃起功能障碍、逆行射精发生率低于TURP组患者（P<0.05）;两组患者术后射精痛和性欲下降的差异无统计学意义（P>0.05）。结论 与TURP相比,TPKEP术中出血量较少,术后对BPH患者性功能的影响较小。